VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors

Breast cancer patients often develop locoregional or distant recurrence years after mastectomy. Understanding the mechanism of metastatic recurrence after dormancy is crucial for improving the cure rate for breast cancer. Here, we characterized a bone metastasis dormancy model to show that aberrant...

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Detalhes bibliográficos
Main Authors: Lu, Xin, Mu, Euphemia, Wei, Yong, Riethdorf, Sabine, Yang, Qifeng, Yuan, Min, Yan, Jun, Hua, Yuling, Tiede, Benjamin J., Lu, Xuemin, Haffty, Bruce G., Pantel, Klaus, Massagué, Joan, Kang, Yibin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241854/
https://ncbi.nlm.nih.gov/pubmed/22137794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.11.002
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