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The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells
Stem cells do not all respond the same way, but the mechanisms underlying this heterogeneity are not well understood. Here, we found that expression of Hes1 and its downstream genes oscillate in mouse embryonic stem (ES) cells. Those expressing low and high levels of Hes1 tended to differentiate int...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725939/ https://ncbi.nlm.nih.gov/pubmed/19684110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1823109 |
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