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NFATc1 Induces Osteoclast Fusion Via Up-Regulation of Atp6v0d2 and the Dendritic Cell-Specific Transmembrane Protein (DC-STAMP)

NFATc1 has been characterized as a master regulator of nuclear factor κB ligand-induced osteoclast differentiation. Herein, we demonstrate a novel role for NFATc1 as a positive regulator of nuclear factor κB ligand-mediated osteoclast fusion as well as other fusion-inducing factors such as TNF-α. Ex...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Kabsun, Lee, Seoung-Hoon, Ha Kim, Jung, Choi, Yongwon, Kim, Nacksung
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Endocrine Society 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725751/
https://ncbi.nlm.nih.gov/pubmed/17885208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0237
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