Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) Regulates Osteoclast Differentiation via the Ca(2+)/NFATc1 axis

DC-STAMP is a multi-pass transmembrane protein essential for cell-cell fusion of osteoclast precursors during osteoclast (OC) development. DC-STAMP−/− mice have mild osteopetrosis and form mononuclear cells with limited resorption capacity. The identification of an Immunoreceptor Tyrosine-based Inhi...

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Pubblicato in:J Cell Physiol
Autori principali: Chiu, Ya-Hui, Schwarz, Edward, Li, Dongge, Xu, Yuexin, Sheu, Tzong-Ren, Li, Jinbo, de Mesy Bentley, Karen L., Feng, Changyong, Wang, Baoli, Wang, Jhih-Cheng, Albertorio-Saez, Liz, Wood, Ronald, Kim, Minsoo, Wang, Wensheng, Ritchlin, Christopher T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386838/
https://ncbi.nlm.nih.gov/pubmed/27723141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25638
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