Quantitative Detection of the M204V Hepatitis B Virus Minor Variants by Amplification Refractory Mutation System Real-Time PCR Combined with Molecular Beacon Technology

Mutations in the highly conserved tyrosine-methionine-aspartate-aspartate (YMDD) motif are frequently associated with resistance to antivirals and represent a major concern in the treatment of hepatitis B virus (HBV) infection. Conventional methods fail to detect minority populations of drug-resista...

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Detalles Bibliográficos
Autores principales: Ntziora, F., Paraskevis, D., Haida, C., Magiorkinis, E., Manesis, E., Papatheodoridis, G., Manolakopoulos, S., Beloukas, A., Chryssoy, S., Magiorkinis, G., Sypsa, V., Hatzakis, A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Virology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725693/
https://ncbi.nlm.nih.gov/pubmed/19553583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00045-09
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