Ultrasensitive Amplification Refractory Mutation System Real-Time PCR (ARMS RT-PCR) Assay for Detection of Minority Hepatitis B Virus-Resistant Strains in the Era of Personalized Medicine

Resistance to antiviral treatment for chronic hepatitis B virus (HBV) has been associated with mutations in the HBV polymerase region. This study aimed at developing an ultrasensitive method for quantifying viral populations with all major HBV resistance-associated mutations, combining the amplifica...

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Detalhes bibliográficos
Main Authors: Ntziora, Fotinie, Paraskevis, Dimitrios, Haida, Catherine, Manesis, Emanuel, Papatheodoridis, George, Manolakopoulos, Spilios, Elefsiniotis, Ioannis, Karamitros, Timokratis, Vassilakis, Alexis, Hatzakis, Angelos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754615/
https://ncbi.nlm.nih.gov/pubmed/23804383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00936-13
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