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Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues

The secreted metalloprotease ADAMTS5 is implicated in destruction of the cartilage proteoglycan aggrecan in arthritis, but its physiological functions are unknown. Its expression profile during embryogenesis and in adult tissues is therefore of considerable interest. β-galactosidase (β-gal) histoche...

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Autors principals: McCulloch, Daniel R., Le Goff, Carine, Bhatt, Sumantha, Dixon, Laura J., Sandy, John D., Apte, Suneel S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725439/
https://ncbi.nlm.nih.gov/pubmed/19250981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gep.2009.02.006
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