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Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues

The secreted metalloprotease ADAMTS5 is implicated in destruction of the cartilage proteoglycan aggrecan in arthritis, but its physiological functions are unknown. Its expression profile during embryogenesis and in adult tissues is therefore of considerable interest. β-galactosidase (β-gal) histoche...

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Bibliografiske detaljer
Main Authors: McCulloch, Daniel R., Le Goff, Carine, Bhatt, Sumantha, Dixon, Laura J., Sandy, John D., Apte, Suneel S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725439/
https://ncbi.nlm.nih.gov/pubmed/19250981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gep.2009.02.006
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