Učitavanje...
The role of amphiphilicity and negative charge in glycoprotein 41 interactions in the hydrophobic pocket
The hydrophobic pocket within the coiled coil domain of HIV-1 gp41 is considered to be a hotspot suitable for small molecule intervention of fusion, although so far it has yielded only μM inhibitors. Previous peptide studies have identified specific hydrophobic interactions and a Lys-Asp salt bridge...
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Glavni autori: | , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2009
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724993/ https://ncbi.nlm.nih.gov/pubmed/19534533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900190q |
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