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The protein tyrosine phosphatase SHP-2 is required for EGFRvIII oncogenic transformation in human glioblastoma cells
Oncogenic EGFRvIII is a naturally occurring oncoprotein and is expressed in about 40–50% of human glioblastomas, particular those that arise de novo. To understand the molecular mechanisms by which this oncoprotein alters transforming phenotypes, and since our previous work indicated that SHP-2 prot...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724964/ https://ncbi.nlm.nih.gov/pubmed/19427850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.05.001 |
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