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A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1β
Interleukin-1β (IL-1β) is overproduced in human and rodent epileptogenic tissue and it exacerbates seizures upon brain application in rodents. Moreover, pharmacological prevention of IL-1β endogenous synthesis, or IL-1 receptor blockade, mediates powerful anticonvulsive actions indicating a signific...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724908/ https://ncbi.nlm.nih.gov/pubmed/18952671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn271 |
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