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Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice

Experimental evidence and clinical observations indicate that brain inflammation is an important factor in epilepsy. In particular, induction of interleukin-converting enzyme (ICE)/caspase-1 and activation of interleukin (IL)-1β/IL-1 receptor type 1 axis both occur in human epilepsy, and contribute...

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Bibliografiska uppgifter
Huvudupphovsmän: Maroso, Mattia, Balosso, Silvia, Ravizza, Teresa, Iori, Valentina, Wright, Christopher Ian, French, Jacqueline, Vezzani, Annamaria
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer-Verlag 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101825/
https://ncbi.nlm.nih.gov/pubmed/21431948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-011-0039-z
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