Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice

Experimental evidence and clinical observations indicate that brain inflammation is an important factor in epilepsy. In particular, induction of interleukin-converting enzyme (ICE)/caspase-1 and activation of interleukin (IL)-1β/IL-1 receptor type 1 axis both occur in human epilepsy, and contribute...

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Detalhes bibliográficos
Main Authors: Maroso, Mattia, Balosso, Silvia, Ravizza, Teresa, Iori, Valentina, Wright, Christopher Ian, French, Jacqueline, Vezzani, Annamaria
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101825/
https://ncbi.nlm.nih.gov/pubmed/21431948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-011-0039-z
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