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Structure Determination of an Inter-strand-type cis-anti Cyclobutane Thymine Dimer Produced in High Yield by UVB Light in an Oligodeoxynucleotide at Acidic pH

UVB irradiation of DNA produces photodimers in adjacent DNA bases and on rare occasions in non-adjacent bases. UVB irradiation (312 nm) of d(GTATCATGAGGTGC) gave rise to an unknown DNA photoproduct in approximately 40% yield at acidic pH of about 5. This product has a much shorter retention time in...

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Detalhes bibliográficos
Main Authors: Su, Dian G. T., Kao, Jeffrey L.-F., Gross, Michael L., Taylor, John-Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724876/
https://ncbi.nlm.nih.gov/pubmed/18680367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8010836
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