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A Rhodium(I)-Xylyl-BINAP Catalyzed Asymmetric Ynamide-[2 + 2 + 2] Cycloaddition in the Synthesis of Optically Enriched N,O-Biaryls

A rhodium(I)-xylyl-BINAP catalyzed asymmetric [2 + 2 + 2] cycloaddition of achiral conjugated aryl ynamides with various diynes is described here. This asymmetric cycloaddition provides a series of structurally interesting chiral N,O-biaryls with excellent enantioselectivity along with a modest dias...

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Detalhes bibliográficos
Main Authors: Oppenheimer, Jossian, Johnson, Whitney L., Figueroa, Ruth, Hayashi, Ryuji, Hsung, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724680/
https://ncbi.nlm.nih.gov/pubmed/20161177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2009.03.078
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