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KLF2 deficiency in T cells results in unrestrained cytokine production and bystander chemokine receptor upregulation
The transcription factor KLF2 regulates T cell trafficking by promoting expression of the lipid binding receptor, S1P(1), and the selectin, CD62L. Recently, it was proposed that KLF2 also represses the expression of chemokine receptors. We confirm the upregulation of the chemokine receptor CXCR3 on...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724594/ https://ncbi.nlm.nih.gov/pubmed/19592277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.05.011 |
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