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Physiologic Deformational Loading Does Not Counteract the Catabolic Effects of Interleukin-1 in Long-Term Culture of Chondrocyte-seeded Agarose Constructs
An interplay of mechanical and chemical factors is integral to cartilage maintenance and/or degeneration. Interleukin-1 (IL-1) is a pro-inflammatory cytokine that is present at elevated concentrations in osteoarthritic joints and initiates the rapid degradation of cartilage when cultured in vitro. S...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724593/ https://ncbi.nlm.nih.gov/pubmed/18823628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2008.06.015 |
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