Sequence determinants of innate immune activation by short interfering RNAs

BACKGROUND: Short interfering RNAs (siRNAs) have been shown to induce immune stimulation through a number of different receptors in a range of cell types. In primary cells, both TLR7 and TLR8 have been shown to recognise siRNAs however, despite the identification of a number of TLR7/8 stimulatory RN...

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Main Authors: Goodchild, Amber, Nopper, Nicole, King, Andrew, Doan, Tram, Tanudji, Marcel, Arndt, Greg M, Poidinger, Michael, Rivory, Laurent P, Passioura, Toby
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724479/
https://ncbi.nlm.nih.gov/pubmed/19630977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-10-40
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