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The Salmonella Effector SptP Dephosphorylates Host AAA+ ATPase VCP to Promote Development of its Intracellular Replicative Niche

Virulence effectors delivered into intestinal epithelial cells by Salmonella trigger actin remodeling to direct pathogen internalization and intracellular replication in Salmonella-containing vacuoles (SCVs). One such effector, SptP, functions early during pathogen entry to deactivate Rho GTPases an...

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Autors principals: Humphreys, Daniel, Hume, Peter J., Koronakis, Vassilis
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724103/
https://ncbi.nlm.nih.gov/pubmed/19286132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2009.01.010
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