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p53 inhibition of AP1-dependent TFF2 expression induces apoptosis and inhibits cell migration in gastric cancer cells

Overexpression of trefoil factor 2 (TFF2) is associated with increased cell migration, resistance to apoptosis, and possibly increased gastric cancer invasion. Dysregulation of p53 is frequently observed in preneoplastic conditions of the stomach. Here, we investigated the effect of p53 on the expre...

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Autores principales: Tu, Shui Ping, Chi, Alfred L., Ai, Walden, Takaishi, Shigeo, Dubeykovskaya, Zina, Quante, Michael, Fox, James G., Wang, Timothy C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724087/
https://ncbi.nlm.nih.gov/pubmed/19541923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90620.2008
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