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Altered thymic selection and increased autoimmunity caused by ectopic expression of DRAK2 during T cell development
Negative regulation of T cell receptor (TCR) signaling is an important mechanism enforcing immunological self-tolerance to prevent inappropriate activation of T cells and thus the development of autoimmune diseases. The lymphoid-restricted serine/threonine kinase DAP-related apoptotic kinase-2 (DRAK...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724075/ https://ncbi.nlm.nih.gov/pubmed/19542440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803530 |
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