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Enhanced T cell apoptosis within Drak2-deficient mice promotes resistance to autoimmunity
Clonal expansion of T cells is vital to adaptive immunity, yet this process must be tightly controlled to prevent autoimmune disease. The serine/threonine kinase DRAK2 is a negative regulator of T cell receptor (TCR) signaling and sets the threshold for the activation of naïve and memory T cells, an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709975/ https://ncbi.nlm.nih.gov/pubmed/19017949 |
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