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IL-10 deficiency unleashes an influenza-specific Th17 response and enhances survival against high dose challenge
We examined the expression and influence of IL-10 during influenza infection. We find that IL-10 does not impact sublethal infection, heterosubtypic immunity, or the maintenance of long-lived influenza antigen depots. However, IL-10-deficient mice display dramatically increased survival compared to...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724021/ https://ncbi.nlm.nih.gov/pubmed/19494257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900657 |
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