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CD25-targeted IL-2 signals promote improved outcomes of influenza infection and boost memory CD4 T cell formation

Interleukin-2 is a pleotropic cytokine with potent pro- and anti-inflammatory effects. These divergent impacts can be directed in vivo by forming complexes of recombinant IL-2 and anti-IL-2 monoclonal antibodies (IL-2C) to target IL-2 to distinct subsets of cells based on their expression of subunit...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Alam, Fahmida, Singh, Ayushi, Flores-Malavet, Valeria, Sell, Stewart, Cooper, Andrea M., Swain, Susan L., McKinstry, K. Kai, Strutt, Tara M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327712/
https://ncbi.nlm.nih.gov/pubmed/32376651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000205
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