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Direct IL-6 signals maximize protective secondary CD4 T cell responses against influenza

Memory T cells can often respond against pathogens that have evaded neutralizing antibodies and are thus key to vaccine-induced protection, yet the signals needed to optimize their responses are unclear. Here, we identify a dramatic and selective requirement for IL-6 to achieve optimal memory CD4 T...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Strutt, Tara M., McKinstry, Karl Kai, Kuang, Yi, Finn, Caroline, Hwang, Ji Hae, Dhume, Kunal, Sell, Stewart, Swain, Susan L.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101150/
https://ncbi.nlm.nih.gov/pubmed/27647834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600033
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