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Noninvasive Molecular Imaging of Hypoxia in Human Xenografts: Comparing Hypoxia-Induced Gene Expression with Endogenous and Exogenous Hypoxia Markers

Tumor hypoxia is important in the development and treatment of human cancers. We have developed a novel xenograft model for studying and imaging of hypoxia-induced gene expression. A hypoxia-inducible dual reporter herpes simplex virus type 1 thymidine kinase and enhanced green fluorescence protein...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: He, Fuqiu, Deng, Xuelong, Wen, Bixiu, Liu, Yueping, Sun, Xiaorong, Xing, Ligang, Minami, Akiko, Huang, Yunhong, Chen, Qing, Zanzonico, Pat B., Ling, C. Clifton, Li, Gloria C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724017/
https://ncbi.nlm.nih.gov/pubmed/18922936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0677
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