Osteoblastic and Osteolytic Human Osteosarcomas can be Studied with a new Xenograft Mouse Model Producing Spontaneous Metastases

There is no animal model that reflects the histological and radiographical heterogeneity of osteosarcoma. We assessed seven osteosarcoma cell lines for their potential to develop orthotopic tumors and lung metastasis in SCID mice. Whereas radiologically, 143B developed osteolytic tumors, SaOS-LM7 de...

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Hlavní autoři: Yuan, Jun, Ossendorf, Christian, Szatkowski, Jan P., Bronk, James T., Maran, Avudaiappan, Yaszemski, Michael, Bolander, Mark E., Sarkar, Gobinda, Fuchs, Bruno
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723944/
https://ncbi.nlm.nih.gov/pubmed/19212826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07357900802491477
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