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2-Methoxyestradiol-induced Cell Death in Osteosarcoma Cells is Preceded by Cell Cycle Arrest

2-Methoxyestradiol (2-ME), a naturally occurring mammalian metabolite of 17β-Estradiol (E(2)), induces cell death in osteosarcoma cells. To further understand the molecular mechanisms of action, we have investigated cell cycle progression in 2-ME-treated human osteosarcoma (MG63, SaOS-2 and LM8) cel...

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Detalhes bibliográficos
Main Authors: Maran, Avudaiappan, Shogren, Kristen L., Benedikt, Michaela, Sarkar, Gobinda, Turner, Russell T., Yaszemski, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821714/
https://ncbi.nlm.nih.gov/pubmed/18384113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21758
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