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Osteoblastic and Osteolytic Human Osteosarcomas can be Studied with a new Xenograft Mouse Model Producing Spontaneous Metastases

There is no animal model that reflects the histological and radiographical heterogeneity of osteosarcoma. We assessed seven osteosarcoma cell lines for their potential to develop orthotopic tumors and lung metastasis in SCID mice. Whereas radiologically, 143B developed osteolytic tumors, SaOS-LM7 de...

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Detalhes bibliográficos
Main Authors: Yuan, Jun, Ossendorf, Christian, Szatkowski, Jan P., Bronk, James T., Maran, Avudaiappan, Yaszemski, Michael, Bolander, Mark E., Sarkar, Gobinda, Fuchs, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723944/
https://ncbi.nlm.nih.gov/pubmed/19212826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07357900802491477
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