Multi-Modality Therapeutics with Potent Anti-Tumor Effects: Photochemical Internalization Enhances Delivery of the Fusion Toxin scFvMEL/rGel

BACKGROUND: There is a need for drug delivery systems (DDS) that can enhance cytosolic delivery of anti-cancer drugs trapped in the endo-lysosomal compartments. Exposure of cells to specific photosensitizers followed by light exposure (photochemical internalization, PCI) results in transfer of agent...

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Hlavní autoři: Selbo, Pål K., Rosenblum, Michael G., Cheung, Lawrence H., Zhang, Wendy, Berg, Kristian
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723936/
https://ncbi.nlm.nih.gov/pubmed/19690617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006691
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