The Antimelanoma Immunocytokine scFvMEL/TNF Shows Reduced Toxicity and Potent Antitumor Activity against Human Tumor Xe nog rafts1

The immunocytokine scFvMEL/TNF, a fusion protein composed of human tumor necrosis factor (TNF) and a single-chain Fv antibody (scFv) scFvMEL targeting the melanoma gp240 antigen, demonstrates impressive cytotoxic effects against human melanoma cell lines in vitro. Pharmacokinetic studies of (125)I-s...

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Detalhes bibliográficos
Main Authors: Liu, Yuying, Zhang, Weihe, Cheung, Lawrence H, Niu, Ting, Wu, Qingping, Li, Chun, Van Pelt, Carolyn S, Rosenblum, Michael G
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592449/
https://ncbi.nlm.nih.gov/pubmed/16790087
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