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Thermodynamic Selection of Steric Zipper Patterns in the Amyloid Cross-β Spine
At the core of amyloid fibrils is the cross-β spine, a long tape of β-sheets formed by the constituent proteins. Recent high-resolution x-ray studies show that the unit of this filamentous structure is a β-sheet bilayer with side chains within the bilayer forming a tightly interdigitating “steric zi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2723932/ https://ncbi.nlm.nih.gov/pubmed/19730673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000492 |
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