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Structure of the cross-β spine of amyloid-like fibrils

Numerous soluble proteins convert to insoluble amyloid-like fibrils having common properties. Amyloid fibrils are associated with fatal diseases such as Alzheimer’s, and amyloid-like fibrils can be formed in vitro. For the yeast protein Sup35, conversion to amyloid-like fibrils is associated with a...

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Detalhes bibliográficos
Main Authors: Nelson, Rebecca, Sawaya, Michael R., Balbirnie, Melinda, Madsen, Anders Ø., Riekel, Christian, Grothe, Robert, Eisenberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479801/
https://ncbi.nlm.nih.gov/pubmed/15944695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03680
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