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The Structural Biology of Protein Aggregation Diseases: Fundamental Questions and Some Answers

Amyloid fibrils are found in association with at least two dozen fatal diseases. The tendency of numerous proteins to convert into amyloid-like fibrils poses fundamental questions for structural biology, and for protein science in general. Among these are: What is the structure of the cross-β spine,...

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Detalhes bibliográficos
Main Authors: Eisenberg, David, Nelson, Rebecca, Sawaya, Michael R., Balbirnie, Melinda, Sambashivan, Shilpa, Ivanova, Magdalena I., Madsen, Anders Ø, Riekel, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017558/
https://ncbi.nlm.nih.gov/pubmed/16981672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar0500618
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