Impaired Axonal Transport in Motor Neurons Correlates with Clinical Prion Disease

Prion diseases are fatal neurodegenerative disorders causing motor dysfunctions, dementia and neuropathological changes such as spongiosis, astroglyosis and neuronal loss. The chain of events leading to the clinical disease and the role of distinct brain areas are still poorly understood. The role o...

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Bibliographic Details
Main Authors: Ermolayev, Vladimir, Cathomen, Toni, Merk, Julia, Friedrich, Mike, Härtig, Wolfgang, Harms, Gregory S., Klein, Michael A., Flechsig, Eckhard
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723930/
https://ncbi.nlm.nih.gov/pubmed/19696919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000558
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