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Impaired Axonal Transport in Motor Neurons Correlates with Clinical Prion Disease

Prion diseases are fatal neurodegenerative disorders causing motor dysfunctions, dementia and neuropathological changes such as spongiosis, astroglyosis and neuronal loss. The chain of events leading to the clinical disease and the role of distinct brain areas are still poorly understood. The role o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ermolayev, Vladimir, Cathomen, Toni, Merk, Julia, Friedrich, Mike, Härtig, Wolfgang, Harms, Gregory S., Klein, Michael A., Flechsig, Eckhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723930/
https://ncbi.nlm.nih.gov/pubmed/19696919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000558
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