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Impaired Axonal Transport in Motor Neurons Correlates with Clinical Prion Disease

Prion diseases are fatal neurodegenerative disorders causing motor dysfunctions, dementia and neuropathological changes such as spongiosis, astroglyosis and neuronal loss. The chain of events leading to the clinical disease and the role of distinct brain areas are still poorly understood. The role o...

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Autori principali: Ermolayev, Vladimir, Cathomen, Toni, Merk, Julia, Friedrich, Mike, Härtig, Wolfgang, Harms, Gregory S., Klein, Michael A., Flechsig, Eckhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723930/
https://ncbi.nlm.nih.gov/pubmed/19696919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000558
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