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Thermodynamic Dissection of Progesterone Receptor Interactions at the Mouse Mammary Tumor Virus Promoter: Monomer Binding and Strong Cooperativity Dominate the Assembly Reaction

Progesterone receptors (PRs) play critical roles in eukaryotic gene regulation, yet the mechanisms by which they assemble at their promoters are poorly understood. One of the few promoters amenable to analysis is the mouse mammary tumor virus gene regulatory sequence. Embedded within this sequence a...

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Hlavní autoři: Connaghan-Jones, Keith D., Heneghan, Aaron F., Miura, Michael T., Bain, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723828/
https://ncbi.nlm.nih.gov/pubmed/18313072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.052
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