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Synthesis of a natural product-inspired eight-membered ring lactam library via ring-closing metathesis
We have prepared a novel speculative eight-membered lactam demonstration library based on the skeletal structure of the potent antitumor marine natural product octalactin A. The basic scaffold was readily constructed in a convergent fashion via ring-closing metathesis chemistry from the correspondin...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2723794/ https://ncbi.nlm.nih.gov/pubmed/18703334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.07.074 |
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