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Histone deacetylase inhibitors —Promising agents for ‘gene-regulating chemoprevention’ and ‘molecular-targeting prevention’ of cancer—

One of the best approaches against cancer is prevention. Inactivation of the p53 or p16(INK4a) genes has been extensively reported in most human cancer cells. Both p53 and p16(INK4a) function as tumor suppressors. Therefore, functional restoration of these molecules is considered to be one of the mo...

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Autors principals: Matsuzaki, Youichirou, Sowa, Yoshihiro, Hirose, Tohru, Yokota, Tomoya, Sakai, Toshiyuki
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723507/
https://ncbi.nlm.nih.gov/pubmed/21432092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/BF02897908
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