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Telomerase activation by histone deacetylase inhibitor in normal cells

Although telomerase activity is known to be regulated mainly at the level of transcription of the human telomerase catalytic subunit (hTERT) gene, the molecular mechanism underlying tumor-specific expression of telomerase remains unclear. Emerging evidence suggests that reversible acetylation of nuc...

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Detalhes bibliográficos
Main Authors: Takakura, Masahiro, Kyo, Satoru, Sowa, Yoshihiro, Wang, Zhuo, Yatabe, Noriyuki, Maida, Yoshiko, Tanaka, Masaaki, Inoue, Masaki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55810/
https://ncbi.nlm.nih.gov/pubmed/11452025
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