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Telomerase activation by histone deacetylase inhibitor in normal cells

Although telomerase activity is known to be regulated mainly at the level of transcription of the human telomerase catalytic subunit (hTERT) gene, the molecular mechanism underlying tumor-specific expression of telomerase remains unclear. Emerging evidence suggests that reversible acetylation of nuc...

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Bibliografske podrobnosti
Main Authors: Takakura, Masahiro, Kyo, Satoru, Sowa, Yoshihiro, Wang, Zhuo, Yatabe, Noriyuki, Maida, Yoshiko, Tanaka, Masaaki, Inoue, Masaki
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC55810/
https://ncbi.nlm.nih.gov/pubmed/11452025
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