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Statistical detection of cooperative transcription factors with similarity adjustment

Motivation: Statistical assessment of cis-regulatory modules (CRMs) is a crucial task in computational biology. Usually, one concludes from exceptional co-occurrences of DNA motifs that the corresponding transcription factors (TFs) are cooperative. However, similar DNA motifs tend to co-occur in ran...

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Detalhes bibliográficos
Main Authors: Pape, Utz J., Klein, Holger, Vingron, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722994/
https://ncbi.nlm.nih.gov/pubmed/19286833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp143
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