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Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model

Abnormal N-methyl-d-aspartate receptor (NMDAR) function has been implicated in the pathophysiology of schizophrenia. d-serine is an important NMDAR modulator, and to elucidate the role of the d-serine synthesis enzyme serine racemase (Srr) in schizophrenia, we identified and characterized mice with...

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Detalhes bibliográficos
Main Authors: Labrie, Viviane, Fukumura, Ryutaro, Rastogi, Anjali, Fick, Laura J., Wang, Wei, Boutros, Paul C., Kennedy, James L., Semeralul, Mawahib O., Lee, Frankie H., Baker, Glen B., Belsham, Denise D., Barger, Steven W., Gondo, Yoichi, Wong, Albert H.C., Roder, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722985/
https://ncbi.nlm.nih.gov/pubmed/19483194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp261
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