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Variation in aggregation propensities among ALS-associated variants of SOD1: Correlation to human disease

To date, 146 different mutations in superoxide dismutase 1 (SOD1) have been identified in patients with familial amyotrophic lateral sclerosis (ALS). The mean age of disease onset in patients inheriting mutations in SOD1 is 45–47 years of age. However, although the length of disease duration is high...

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Bibliografiske detaljer
Main Authors: Prudencio, Mercedes, Hart, P. John, Borchelt, David R., Andersen, Peter M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722984/
https://ncbi.nlm.nih.gov/pubmed/19483195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp260
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