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Variation in aggregation propensities among ALS-associated variants of SOD1: Correlation to human disease

To date, 146 different mutations in superoxide dismutase 1 (SOD1) have been identified in patients with familial amyotrophic lateral sclerosis (ALS). The mean age of disease onset in patients inheriting mutations in SOD1 is 45–47 years of age. However, although the length of disease duration is high...

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Main Authors: Prudencio, Mercedes, Hart, P. John, Borchelt, David R., Andersen, Peter M.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722984/
https://ncbi.nlm.nih.gov/pubmed/19483195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp260
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