Sensitive and Specific Detection of Early Gastric Cancer Using DNA Methylation Analysis of Gastric Washes

BACKGROUND & AIMS: Aberrant DNA methylation is an early and frequent process in gastric carcinogenesis and could be useful for detection of gastric neoplasia. We hypothesized that methylation analysis of DNA recovered from gastric washes could be used to detect gastric cancer. METHODS: We studie...

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Hauptverfasser: Watanabe, Yoshiyuki, Kim, Hyun Soo, Castoro, Ryan J., Chung, Woonbok, Estecio, Marcos R. H., Kondo, Kimie, Guo, Yi, Ahmed, Saira S., Toyota, Minoru, Itoh, Fumio, Suk, Ki Tae, Cho, Mee-Yon, Shen, Lanlan, Jelinek, Jaroslav, Issa, Jean-Pierre J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722957/
https://ncbi.nlm.nih.gov/pubmed/19375421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.02.085
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