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Reduction of estrogen-induced transformation of mouse mammary epithelial cells by N-acetylcysteine

A growing number of studies indicate that breast cancer initiation is related to abnormal estrogen oxidation to form an excess of estrogen-3,4-quinones, which react with DNA to form depurinating adducts and induce mutations. This mechanism is often called estrogen genotoxicity. 4-catechol estrogens,...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Venugopal, Divya, Zahid, Muhammad, Mailander, Paula C, Meza, Jane L., Rogan, Eleanor G., Cavalieri, Ercole L., Chakravarti, Dhrubajyoti
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722841/
https://ncbi.nlm.nih.gov/pubmed/18226522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2007.12.003
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