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Reduction of estrogen-induced transformation of mouse mammary epithelial cells by N-acetylcysteine
A growing number of studies indicate that breast cancer initiation is related to abnormal estrogen oxidation to form an excess of estrogen-3,4-quinones, which react with DNA to form depurinating adducts and induce mutations. This mechanism is often called estrogen genotoxicity. 4-catechol estrogens,...
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| Main Authors: | , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2007
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722841/ https://ncbi.nlm.nih.gov/pubmed/18226522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2007.12.003 |
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