The role of polycyclic aromatic hydrocarbon-DNA adducts in inducing mutations in mouse skin

Polycyclic aromatic hydrocarbons (PAH) form stable and depurinating DNA adducts in mouse skin to induce preneoplastic mutations. Some mutations transform cells, which then clonally expand to establish tumors. Strong clues about the mutagenic mechanism can be obtained if the PAH-DNA adducts can be co...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Chakravarti, Dhrubajyoti, Venugopal, Divya, Mailander, Paula C., Meza, Jane L., Higginbotham, Sheila, Cavalieri, Ercole L., Rogan, Eleanor G.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254211/
https://ncbi.nlm.nih.gov/pubmed/17931959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2007.08.007
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы