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CCL5/RANTES gene deletion attenuates opioid-induced increases in glial CCL2/MCP-1 immunoreactivity and activation in HIV-1 Tat exposed mice

To assess the role of CC-chemokine ligand 5 (CCL5)/RANTES in opiate drug abuse and human immunodeficiency virus type 1 (HIV-1) comorbidity, the effects of systemic morphine and intrastriatal HIV-1 Tat on macrophage/microglial and astroglial activation were assessed in wild-type and CCL5 knockout mic...

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Detalles Bibliográficos
Main Authors: El-Hage, Nazira, Bruce-Keller, Annadora J., Knapp, Pamela E., Hauser, Kurt F.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722754/
https://ncbi.nlm.nih.gov/pubmed/18815890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-008-9127-1
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