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Cerebral Cavernous Malformations: Somatic Mutations in Vascular Endothelial Cells
OBJECTIVE: Germline mutations in three genes have been found in familial cases of cerebral cavernous malformations (CCM). We previously discovered somatic and germline truncating mutations in the KRIT1 gene supporting the “two-hit” mechanism of CCM lesion formation in a single lesion. The purpose of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722441/ https://ncbi.nlm.nih.gov/pubmed/19574835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/01.NEU.0000348049.81121.C1 |
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