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A model for DNA polymerase switching involving a single cleft and the rim of the sliding clamp

The actions of Escherichia coli DNA Polymerase IV (Pol IV) in mutagenesis are managed by its interaction with the β sliding clamp. In the structure reported by Bunting et al. [EMBO J (2003) 22:5883–5892], the C-tail of Pol IV contacts a hydrophobic cleft on the clamp, while residues V303–P305 reach...

詳細記述

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書誌詳細
主要な著者: Heltzel, Justin M. H., Maul, Robert W., Scouten Ponticelli, Sarah K., Sutton, Mark D.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722325/
https://ncbi.nlm.nih.gov/pubmed/19617571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903460106
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